Abstract
Background: Laryngopharyngeal reflux (LPR) is a prevalent disorder. The aim of the present retrospective cohort study was to evaluate oropharyngeal pH-monitoring using a novel scoring system for LPR. Methods: In a total of 180 consecutive patients with possible LPR, reflux symptom index (RSI), reflux finding score (RFS), oropharyngeal pH-monitoring and transnasal esophagoscopy were carried out for further investigation. Results: In our series, 99 (55%) patients had severe LPR, 29 (16%) cases presented with moderate and 23 (13%) with mild severity, 9 (5%) subjects revealed neutral values, and 7 (4%) individuals were alkaline, while 13 (7%) patients had no LPR. In detecting LPR, the sensitivity, specificity and accuracy of oropharyngeal pH-monitoring was 95%, 93% and 94%, respectively. Conclusion: Oropharyngeal pH-monitoring is a reliable tool in the assessment of LPR, but the pH graphs have to be precisely analyzed and interpreted in context with other validated diagnostic tests.
Highlights
As traditional impedance pH-metry has failed in the throat due to false-positive and -negative results, the gold standard for gastroesophageal reflux (GER)
The downward-facing drop-shaped antimony tip of the Restech probe avoids being covered by mucus or food, prevents it from drying out, is capable of detecting both liquid and gaseous droplets in the pharynx and does not require contact with fluid or tissue for electrical continuity. This would make the Restech probe an ideal instrument for the detection of extraesophageal reflux, but there is still a need to further investigate the diagnostic value of this method, which was the main goal of this study [18,24]
Laryngopharyngeal reflux (LPR) is a prevalent disorder in the general population, and a novel scoring system has recently been proposed for its diagnosis
Summary
The aim of the present study was to evaluate oropharyngeal pH-monitoring in the assessment of LPR, identifying possible pitfalls and developing strategies to avoid them, while the Horvath Score served as the gold standard for LPR diagnosis
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