Evaluation of Organophosphorus Poisoning: Case Series

Abstract

Organophosphate insecticide compounds inhibit both acetyl cholinesterase and pseudocholinesterase activities. Acute organophosphate insecticide poisoning can manifest three different phases of toxic effects namely, acute cholinergic crisis, intermediate syndrome (IMS), and delayed polyneuropathy. Diagnosis is based on history of exposure and clinical manifestations. Management is beneficial with supportive measures along with specific antidotes. In this case reports, two patients with organophosphate insecticide poisoning are described. Both patients tried to commit suicide by ingesting an unknown amount of organophosphorus poison and both of them have developed intermediate syndrome. But one patient collapsed due to cardiac arrest and other patient was discharged with no complaints. Treatment for both patients mainly included atropine and parlidoxime.