Abstract

Chlorhexidine gluconate mouthwash has a poor taste during and after rinsing which makes its users dissatisfied. Therefore, the product must be improved to have a better taste and still retain its effectiveness against oral pathogens. To evaluate in vitro antimicrobial activity and toxicity effects of Newly formulated chlorhexidine mouthwash. The antimicrobial activity of the mouthwash was evaluated by Agar well diffusion method against the tested microorganisms. The toxicity test was performed by using the MTT assay. The new formula has the potential to treat and prevent oral and throat infections. The newly developed Chlorhexidine mouthwash can be considered safe for oral usage.

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