Abstract

Iron deposition in the heart and liver are considered to play a central role in the long term outcome of ex-thalassemic hematopoetic stem cell transplantation (HSCT) survivors. There is a lack of correlation between heart and liver iron load. Serum ferritin and liver iron values have almost no predictive value for cardiac iron deposition. This study was conducted in order to assess myocardial and hepatic iron concentrations using T2* MRI and detection of any effect of transplantation itself and chelation therapy in ex-thalassemic patients who survived beyond six months.

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