Evaluation of mineral metabolism of immunocorrected boars during castration

Abstract

The article presents data on the effect of castration on changes in indicators reflecting mineral metabolism. The work was performed on 14 boars (aged 5 months) divided into two groups ‒ control and experimental ones (n = 7 in each). Before castration by an open method, all animals were intramuscularly injected with ketoject; and in the postoperative period, medical support consisted of repeated use of the abovementioned drug, as well as cobactan and hipratopic. The boars of the experimental group were additionally injected with thymogen. Blood sampling was performed before the surgery, on the 14th and 30th day after it, the serum was obtained using the conventional method. The content of calcium, phosphorus, sodium, potassium, chlorine, magnesium was evaluated.It was found that the indicators of sodium, potassium, chlorine and magnesium before castration of boars were within the physiological norm in both groups, while the indicators of both calcium and phosphorus exceeded physiological norm in the control and experimental groups by 1.46 ‒ 1.51 and 1.14 ‒ 1.22 times, respectively.Further dynamics of calcium and phosphorus was accompanied (in the catabolic phase) by hypocalcemia, a decrease in the level of phosphorus to reference values, in the anabolic phase by normalization of the calcium content against the background of a slight excess increase in phosphorus.The use of thymogen in the experimental group contributed to a decrease in the intensity of changes on the 14th day and normalization of calcium and phosphorus on the 30th day. There were no significant fluctuations in the dynamics of sodium and chlorine. Potassium levels in both groups in the catabolic phase exceeded both the initial and standard values (mostly in the control), in the anabolic phase this trend persisted in relation to the control against the background of normalization in the experimental group. The content of magnesium in the blood serum of boars was characterized by positive dynamics: indicators were below the norm before castration, the reference values were subsequently noted in the control group on the 14th day, in the experimental group ‒ on the 30th. The presented research results indicate that the protective effect of thymogen in optimizing mineral metabolism during castration of boars is mainly realized at the level of calcium and phosphorus dynamics.