Evaluation of microcirculatory tissue systems after cosmetic procedures

Abstract

Relevance . Not only microvasculature and derma are involved in the involution processes. The involution also effects on the all components of skin resulting in its function and structure alterations. By this reason we can speak about the disturbances of microcirculatory tissue system. The aim of this work was a comparative assessment of cosmetic equipment (PDL, IPL), mesotherapy and external skin care therapy in cosmetology patients by the functional state of microcirculatory tissue system of facial skin. Materials and methods . 62 women after mesotherapy, equipment cosmetology and professional external therapy of facial skin were involved in the exploration. We used the laser Doppler flowmetry and laser fluorescence spectroscopy for assessment the microcirculation, lymph flow and the oxidative metabolism coenzymes. Results . Peripheral blood flow did not change significantly, as the lymph flow rate in the control and experimental groups. Nutritional blood flow increased significantly to 12,11 [11,17; 14,17] and 11,88 [10,59; 12,28] in patients after injection and external therapy (p<0,001 and p=0,010, respectively). The NADH fluorescence amplitudes significantly decreased in all groups compared with the control (p<0,001, p=0,002, p=0,008), and FAD decreased only after injection therapy (p=0,022). Conclusions . The injections for correction the age-related skin changes improve the nutrition and normalize tissue metabolism. Our results can be useful in comparative assessment of different ways of the age-related skin changes cosmetic treatment.