Abstract
Abstract AIM The aim of this study was to investigate the lactate response in physically inactive hypertensive women submitted to the treadmill maximal lactate steady state (MLSS) protocol. METHODS Twenty-two hypertensive women (40 - 64 years) performed a familiarization period of walking on the treadmill following by one incremental test for estimating the initial workload for exercise testing. MLSS protocol was composed by walking in a treadmill during thirty minutes with fixed velocity in 5.5 km/h. Incline was used for determination of the intensity of each volunteer. Blood samples were collected from the ear lobe in the rest period, minute 10th and at the end of the test (minute 30th or at exhaustion time point) for lactate analysis. RESULTS Hypertensive women showed a lower lactate concentration at MLSS (3.25 ± 0.81 mmol/L) as compared with data obtained in the literature (4 mmol/L), approximately 18.8%. Neither inclines nor age affected MLSS parameters in the population. A positive and strong correlation was found between incline and MLSS, as well as incline and lactate level at minute 30th, even when adjusted by age factor. CONCLUSION Physically inactive hypertensive women show a lower MLSS than the average established in the literature but within the range of variations previously reported. Furthermore, a higher MLSS incline correlates positive and directly with higher lactate concentrations for the same aerobic capacity regardless of age.
Highlights
Stroke, myocardial infarct and coronary artery disease are the main complication of arterial hypertension, representing a high cost for the public health system[1]
Hypertensive women were overweight and the peak of O2 consumption was in a normal range for physically inactive middle-aged women
The prevalence of arterial hypertension increases abruptly during climacteric period and it is well established the relevance of exercise training on blood pressure regulation[23]
Summary
Myocardial infarct and coronary artery disease are the main complication of arterial hypertension, representing a high cost for the public health system[1]. The knowledge about the metabolic predominance during different intensities and types of physical exercise constitutes a factor of great importance for the individualized prescription of training[5] This becomes fundamental and relevant in rehabilitation programs for hypertensive individuals, given the need in adopting safe intensities for the practice as well as promoting effective benefits on the cardiovascular system. Several studies have investigated distinct methodology that could clearly and accurately characterize the transition between the metabolic stages during exercise[6–9] Among these methods, the analysis of the lactate concentration and determination of its respective threshold has been widely used because it is considered one of the best biomarker in the analysis of the individual responses from the metabolic point of view, allowing to determine aerobic and anaerobic predominance as well as the evolution of the individual response to exercise training programs[10]
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