Abstract

Evaluation of malaria transmission intensity using antibody responses to Plasmodium falciparum merozoite surface protein-119 after vector control in western Kenya

Highlights

  • Indoor residual spraying (IRS) have reduced malaria cases and deaths in many malaria endemic areas

  • Serum from 5,839 children and adults collected during cross-sectional surveys conducted before and after vector control were tested for anti

  • Antibody levels were compared as continuous optical density (OD)

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Summary

Introduction

The scale up of malaria control strategies such us insecticide-treated bednets (ITNs) and indoor residual spraying (IRS) have reduced malaria cases and deaths in many malaria endemic areas. It is difficult to accurately quantify the reduction in the malaria burden in endemic areas because the common methods of assessing transmission intensity are imprecise, unreliable and costly. There is need to evaluate better alternatives for estimating malaria disease transmission. Antibody levels to Plasmodium falciparum merozoite surface protein-Ire (MSP-b9)

Results
Conclusion

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