Evaluation of low intensity laser's action on silicone mammary implant pseudocapsules in rats

Aristides Palhares,Claudia Helena Pellizzon,Carlos Roberto Padovani,Silvana Artioli Schellini,Patrícia Dorsa

doi:10.1590/s0102-86502009000100003

Abstract

To evaluate the effect of low intensity laser on the pseudocapsule contraction that occurs around silicone implants. 60 male rats divided in two experimental groups received a silicone implant in the subcutaneous of the dorsal region. Group I: animals received implants in the subcutaneous dorsal region and did not receive any treatment; Group II: animals received seven irradiation sessions with low intensity laser after they had received subcutaneous implants. Thirty, 60 and 180 days after the surgery, tonometric evaluation of the implants was conducted. After that, the animals were sacrificed, study material was removed and prepared for histological examination. The thickness of the pseudocapsule and the inflammatory reaction were morphometrically quantified. Data obtained were statistically analyzed using the Variance method, and Tukey's Test(P<0.0 5). Group II animals had significant lower pressure. The histological study did not show a significant difference between the groups, but only a higher number of swollen vessels in Group II. The thickness of pseudocapsule around Group II's implants lower than in Group I. The low intensity laser modify tissue's reparation process around the implants suggesting it may be useful to model contractures that are formed around silicone implants.

Highlights

Silicone breast implants modifications have been made that aim at reducing the contraction entail problems like fibrous encapsulation and when tissue is of such capsules but a definitive solution to the problem is yet to contracted, the breast hardens and the implant can fold
The tonometric values of Group I were higher on 180th day, with a statistically significant difference
Higher pressure was observed in implants in Group I, in comparison with Group II, 180 days after they were include (Table 1)

Summary

Introduction

Silicone breast implants modifications have been made that aim at reducing the contraction entail problems like fibrous encapsulation and when tissue is of such capsules but a definitive solution to the problem is yet to contracted, the breast hardens and the implant can fold. To put it better, pseudocapsules, occur in a normal process of tissue reparation: conjunctive tissue tries to isolate the foreign body that is being introduced into the organism. A number of methods drawing on the two theories have been tried to control the process of pseudocapsule formation, e.g., application of antibiotics,[3] corticosteroids[4] and even physical methods like modification of the surface structure of implants; employment of pulsed electromagnetic energy[5] and of ultrasound.[6].

Methods

Results

Conclusion