Evaluation of Low and High Flow Anesthesia Methods' Effects on Perioperative Hemodynamics, Depth of Anesthesia and Postoperative Recovery in Patients Undergoing Abdominal Surgery

Abstract

Objective: The safe implementation of low-flow anesthesia has greatly facilitated, because of the anesthesia machines monitors that analyze the anesthetic gas composition detailed way, increase the knowledge of anesthetics. In this research; we aimed to compare the effects of high and low-flow general anesthesia methods on the peroperative hemodynamics, anesthesia depth and postoperative recovery time in patients with abdominal surgery in the presence of bispectral index monitoring. Methods: ASA I-II, 40 patients; 18 - 75 ages, who will have abdominal surgery were randomly divided into two groups, after the approval of the ethics committee (2016 - 06/02) and the patients. Anesthesia induction was performed with 6 mg/kg thiopental sodyum, 1 μg/kg remifentanil and 0.5 - 20 μg/kg/min remifentanil infusion, 4 - 6% desflurane after routine ECG, blood pressure, SpO2 and BIS monitorization to all patients. In the low-flow group after the first 10 min 4 lt/min fresh flow, the flow was reduced to 1 lt/min. Values of the heart rate, MBP, SpO2, FiO2, BIS, tympanic temperature at before induction and after intubation and the minutes of 15th, 30th, 45th, 60th, 90th,120th are recorded. Lactate and COHb values were measured in blood gas analyzes performed at 30th and 90th minutes. Results: When SpO2 and FiO2 values measured in different time periods of the individuals in both two groups were compared, differences between the minutes of 30th, 45th, 60th, 90th, 120th were significant. Conclusion: In this research; it is revealed that low-flow anesthesia which has advantages in many aspects can be used safely like high flow anesthesia when applied with adequate information equipment, appropriate anesthesia devices and necessary monitorizations.