Evaluation of Lipid Profile in H. Pylori Infected Coronary Artery Disease Patients

Abstract

Increase in low density lipoprotein level and decrease in high density lipoprotein level result to coronary artery disease. Metabolism of lipids regulated during host response to H. pylori infection. Objective: To analyze the serum levels of lipid profile in H. pylori infected coronary artery disease patients. Methods: It was a comparative Cross-Sectional study. This study was done at the Department of Biochemistry, Peoples University of Medical Health Sciences for Women (PUMHSW) from 1st July 2022 to 15th December 2022. A sample of 60 subjects was divided into 2 groups. Group A (Control) comprised of 30 subjects and group B (cases) of 30 subjects. 5 mL of blood from each participant was collected under aseptic conditions. For the Lipid profile, 2 mL of the blood was collected in the Gel test tubes. A Spectrophotometer was used to perform the lipid profile. For the data analyzes SPSS Version-22.0 was used. Results: In this study we found that Helicobacter pylori positive subjects have higher levels of serum LDL.C, Triglycerides and total cholesterol. The outcomes of present research showed that H. pylori is associated with low level of HDL-C. The present study results shown an association among H. pylori infection and coronary artery possibility influence. Conclusions: We concluded in this study that serum levels of lipid profile become worse in positive H. pylori infected patients as compared to the control group participants which were negative H. pylori with coronary artery disease.