Evaluation of leftventricular rotation and twist in uremia patients by two-dimensional ultrasound speckletracking imaging

Abstract

：Objective To analyze theleft ventricular(LV) rotation and twist by two-dimensional ultrasound speckle-trackingimaging(STI),and evaluate the correlation between twist and other components of LVcontraction in uremia patients. Methods Twenty-nine uremia patients and twenty-ninehealthy volunteers were included. High frame rate two-dimensional images were recordedfrom the left ventricular short-axis views both of the basal and apical planes. Segmentaland global LV rotation were recorded at both The peak systolic LV twist was significantlydecreased in uremia patients(P <0. 001). The loss of LV twist occurred mainly by theimpairment of maximal global counterclockwise apical rotation(P <0. 001),and wasaugmented by somewhat less reduction in global clockwise basal rotation although thedifferences was not significantly reduced(P<0.01), while only the posterior andinferior of the basal plane was significantly fraction(r=0.645,P=0.000), LV end-diastolicvolume (r=-0.549,P=0.002), LV end-systolic volume(r=-0.673, P = 0.000) in uremia patients.Conclusions STI enables quantification of segmental and global LV rotation in an objectivemanner in uremia patients,and provides a new method for evaluation of segmental and globalLV systolic function.