Abstract

Objective To evaluate regional and global systolic function of left ventricle (LV) after mitral valve replacement(MVR) of different methods by 2-dimensional strain (2DS).Methods According to the operational method whether preserve the posterior leaflet and its subvalvular apparatus,48 patients who underwent MVR were divided into two groups,the preservation group (group A) and the resection group (group B).Echocardiography was examinated before and after MVR and the apical four-chamber view,two-chamber view and long-axis view of LV were acquired.Regional peak strain (Sp) and global strain (GS) of LV longitudinal movement were analysed by 2DS software.Results ①Compared to preoperation,the Sp in basal segment of posterior septum and inferior wall and middle segment of lateral wall in group A increased significantly ( P <0.01 or P <0.05).The Sp of group B were improved in both basal and middle segments of posterior septum ( P <0.05),while declined in middle segment of lateral wall and anterior wall,basal segment of lateral wall and apical segment of anterior wall significantly (P <0.01 or P <0.05).②Compared with group A,subtractions between preoperative and postoperative Sp of group B decreased in middle segment and apical segment of anterior wall,middle segment of lateral wall and middle segment of inferior wall significantly ( P <0.01 or P <0.05).③The GS of group A increased significantly ( P <0.05),while that in group B tended to reduce with no statistical significance ( P >0.05).Compared with group A,subtractions between preoperative and postoperative GS of group B droped significantly (P < 0.05).Conclusions Appropriate preservation of the posterior leaflet and its subvalvular apparatus has morebeneficial effect in improving the early regional and global function of LV after surgery,which would be recommended in MVR.Early regional and global systolic function of LV after MVR could be accurately evaluated by 2DS relatively,which has the application value of guiding clinical treatment and estimating prognosis. Key words: Echocardiography; Mitral valve stenosis; Heart valve prosthesis implantation; Ventricular function,left; Two-dimensional strain

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