Evaluation of left ventricular segmental function in patients with coronary disease before and after percutaneous coronary intervention by real-time three-dimentional echocardiography

Abstract

Objective To assess left ventricular segmental function in patients with coronary heart disease(CHD)before and after percutaneous coronary intervention(PCI)using volume-time curves(VTCs)and Bulls Eye images from real-time three-dimentional echocardiography(RT-3DE).Methods Thirty-two patients with CHD confirmed by coronary angiography were undergone RT-3DE before and 1 week after PCI,respectively.The 17-segmental VTCs and Bulls Eye images from RT-3DE were obtained and analyzed by the on-line Qlab software.Parameters including the numbers of dyskinetic segments,regional diastolic volume(rEDV),regional systolic volume(rESV),regional ejection fractions(rEF)and the ejection fractions of regional stroke volume to global diastolic volume(rgEF)were compared.Thirty normal subjects were selected as control group.Results Compared with control group,the CHD group before PCI showed more dyskinetic segments(5.2±1.8),and the parameters of regional heart function reached high significant difference(P<0.01).By contrast with CHD group before PCI,the numbers of dyskinetic segments reduced and the parameters of regional heart function impmved after PCI(P<0.05).Conclusions Seventeen-segmental volume-time curves(VTCs)and Bull's Eye images from RT-3DE can assess the effective changes of regional heart function resulted from PCI qualitatively and quantitatively,which providing another useful modality for evaluating the effection of PCI in CHD patients. Key words: Echocardiography; real-time three-dimentional; Coronary disease; Angioplasty,transluminal,percutaneous coronary