Evaluation of left ventricular myocardial remodeling in simple obesity children with three-dimensional speckle tracing imaging

Abstract

Objective To evaluate the left ventricular remodeling in children with simple obesity quantitatively using three dimensional speckle tracing imaging (3D-STI). Methods From May 2017 to October 2018, 43 obese children were selected as an obese group, and 38 overweight children as an overweight group; 45 healthy children who had normal physical examination in the same period were selected as a control group. The left ventricular end-systolic volume (LVESV), left ventricular end-diastolic volume (LVEDV), left ventricular ejection fraction (LVEF), left ventricular global longitudinal strain (GLS), left ventricular global circumferential strain (GCS), and left ventricular global radial strain (GRS) were examined by two-and three-dimensional echocardiography, and compared among the three groups. The correlation of 3D-STI parameters with BMI and left ventricular mass (LVM) was analyzed by Pearson. Results The BMI, systolic blood pressure, LVESV, LVEDV and LVM were significantly higher while the GLS, GRS, and GCS were significantly lower in the obesity group and the overweight group than in the control group (all P<0.05). The GCS was significantly lower in the obese group than in the overweight group (P<0.05). Pearson correlation analysis showed that GLS, GRS and GCS positively correlated with BMI and LVM (all P<0.01). Conclusions 3D-STI can be used to evaluate the changes of the systolic function of children with simple obesity. Its sensitivity in assessing early myocardial changes is higher than two-dimensional echocardiography’s. Key words: Three-dimensional speckle tracing imaging; Obesity; Myocardial remodeling; Left ventricle; Evaluation value