Abstract

Objective:To explore the evaluation of left ventricular diastolic function (LVDF) in patients with coronary heart disease (CHD) using ultrasound images (UI) combined with electrocardiogram (ECG) on bilateral filtering image noise reduction algorithm (BFINRA).Methods:A BFINRA was constructed, and 60 subjects who were investigated were divided into a control group (CG) from June 2019 to November 2019 in Taizhou People’s Hospital, a myocardial infarction group (MIG), and an angina pectoris group (APG). The patient’s LVDF was examined by two-dimensional electrophoresis (2DE) and real-time three-dimensional echocardiography (RT-3DE) combined with ECG. The results showed BFINRA could improve UI quality.Results:Clinical data indicated there were no substantial differences in age, gender, and fasting blood glucose of all subjects. 2DE examination results showed the left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), and early diastolic mitral blood flow velocity / early diastolic mitral annulus velocity (E/E’) of MIG were much higher than CG (P<0.05), while the left ventricular ejection fraction (LVEF), E / late diastolic mitral blood flow velocity (E/A) and E’ peak value were sharply decreased (P<0.05);LVESV and E/E’ of APG were increased dramatically (P<0.05), while E peak, E/A and E’ peak were decreased greatly. RT-3DE examination results indicated LVEDV and LVESV of MIG were considerably higher than CG (P<0.05), while LVEF and macrophage resistance factor (MRF) were enormously decreased (P<0.05);LVEDV and LVESV of APG were greatly increased (P<0.05). However, LVEF and MRF were not changed significantly (P>0.05). LVEDV had a remarkable difference (P<0.05), but LVESV and LVEF had no obvious differences (P>0.05). The electrocardiogram results illustrated the increase in QT dispersion (QTd) of MIG and APG was statistically significant (P<0.05) compared with CG, while the negative increase of P-wave terminal force in lead V1 (PTFV1) also had a statistical significance (P<0.05). Correlation analysis revealed that MRF and PTFV1 had positive correlation, while MRF and QTd showed a negative correlation.Conclusion:The combination of UI and ECG could better assess LVDF in CHD patients.

Highlights

  • RT-3DE has greatly improved the application of ultrasound diagnosis in the evaluation of cardiac morphology and function, which does not rely on geometric assumptions and can reflect the dynamic changes of the heart chamber volume in real-time to obtain the left ventricular volume-Pak J Med Sci September 2021 (Speical Issue Online) Vol 37 No 6 www.pjms.org.pk 1699time curve (VTC).[1,2,3] RT-3DE provides a noninvasive, simple, and new approach to evaluate heart function

  • Based on the diagnosis results, all subjects were divided into 3 groups: the control group (CG) (20 subjects), myocardial infarction group (MIG) (19 subjects), and angina pectoris group (APG) (21 subjects)

  • 3, and 4, the measurement results of left ventricular diastolic function (LVDF) were illustrated by the 2D echocardiography. It showed that the left ventricular end-diastolic volume (LVEDV), left ventricular end-systolic volume (LVESV), and early diastolic mitral annulus velocity (E/E)’ of the patients in MIG were enormously improved (P

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Summary

Introduction

RT-3DE has greatly improved the application of ultrasound diagnosis in the evaluation of cardiac morphology and function, which does not rely on geometric assumptions and can reflect the dynamic changes of the heart chamber volume in real-time to obtain the left ventricular volume-. Time curve (VTC).[1,2,3] RT-3DE provides a noninvasive, simple, and new approach to evaluate heart function. The bilateral filtering can optimize echocardiography, providing more accurate information. There are more speckle noises in ultrasound images, so that the effectiveness of doctors’ diagnosis of diseases and evaluation of curative effects are affected.[4,5,6] At present, many algorithms have been applied to the denoising of medical ultrasound images, such as wavelet transform, non-average denoising, and bilateral filtering denoising.[7,8] Among them, bilateral filtering can optimize the echocardiography and provide more accurate information

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