Evaluation of larvicidal effect of Dysoxylum binectariferum Hook against Anopheles stephensi Liston, Culex quinquefasciatus Say and Aedes aegypti L.

Abstract

In the present study larvicidal activity of methanolic extract of leaf of Dysoxylum binectariferum Hook (Meliaceae) was assessed against 3 rd & 4 th instar larvae of 3 mosquito vector species Anopheles stephensi, Culex quinquefasciatus and Aedes aegypti. The bioassays revealed that Cx. quinquefasciatus was most sensitive species. The dose mortality data were subjected to log probit regression analysis to determine median lethal concentrations, LC 50 and LC 90 after 24-hour exposure. The highest mortality was observed in Cx. quinquefasciatus [LC 50 = 340 ppm, (95% CI: 240 - 460 ppm); LC 90 = 600 ppm (CI: 390- 1083 ppm)] followed by Ae. aegypti [LC 50 = 3236 ppm, (CI: 2500-4180 ppm); LC 90 = 55410 ppm (CI: 34720-103910 ppm)] and An. stephensi [LC 50 = 13460 ppm (CI: 12840-14180 ppm); LC 90 = 18010 ppm (CI: 16650-20360 ppm)]. As a larvicide, leaf extracts of Dysoxylum binectariferum could be explored further.