Evaluation of Kidney Functions After Nephrectomy: Single Center Experience

Abstract

Aim: In this study, it was aimed to investigate the kidney function, hypertension development and proteinuria in individuals with only one kidney . Patients and Methods: The study included 96 patients who had previously undergone nephrectomy with the causes of nephrolithiasis and chronic pyelonephritis-induced nonfunctional kidney, RCC (Renal Cell carcinoma), trauma, and donor nephrectomy among 17800 patients who applied to the Siirt State Hospital Nephrology and Urology outpatient clinics between January 2016 and December 2019. The data of the patients were obtained from patient files database retrospectiv ely. Results: A total of 96 patients, 45 female and 51 male, were included in the study. 23 (24%) of the patients had donor nephrectomy (DN), and 73 (76%) had nephrectomy (DE) due to nephrolithiasis, chronic pyelonephritis, trauma, and renal cell cancer (RCC). The patients were divided into two groups as those who underwent DN and DE due to other etiologies. Between DN and DE group, there was no statistically significant difference in terms of mean age, distribution of gender, presence of HT before nephrectomy, DM, presence of hematuria and new onset proteinuria (P> 0.05). Compared to the DN group, the frequency of new onset in CKD and HT development was significantly higher DE group. Conclusion: Nephrectomy is a risk factor for the development of CKD, proteinuria and hypertension. Therefore, preventive measures should be taken in a timely manner to reduce the prevalence of nephrectomies due to benign diseases.