Abstract
The present study was undertaken to evaluate the anti-inflammatory activity of the leave extracts of Carissa spinarum. In ancient literature the medicinal values of Carrissa spinarum and it is useful in treatment of rheumatism, purgative and snake repellent. Dried pulverized leaves of C.spinarum were extracted with petroleum ether, chloroform, ethanol and distilled water by using soxhlet apparatus separately. Formalin induced rat hind paw edema method was used for determination of anti-inflammatory activity. Group I was taken as normal control and the group II as formalin control. Group III was treated with the standard drug analgin. The petroleum ether extract, chloroform extract, alcoholic extract and aqueous extract of C. spinarum leaves 200 mg/kg were feed to group IV, V, VI and VII respectively. All extracts exhibited significant anti-inflammatory activity, but aqueous extract produces maximum activity compared to other extracts of C. spinarum. It has been concluded that aqueous extract of C. spinarum leaves having good anti-inflammatory activity against formalin induced rat paw edema.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
