Abstract

Objective To investigated the value of intraoperative ultrasonography in guiding the surgical approach,improving the total resection rate of the tumor,and the survival time of patients who underwent resection of cerebral gliomas.Methods One hundred and ninteen patients with cerebral gliomas (pathologically confirmed) comprised the study groups.Patients who underwent intraoperative ultrasoundguided surgery were followed up for 6-60 months.In addition,randomly selected low and high grade cerebral glioma patients (all 30 cases of which were without intraoperative ultrasonography guidance) served as the control groups.Follow up included survival time,and the differences in survival time between the study groups and control groups were statistically analyzed.Results Complete follow-up data were obtained for 101 of 119 cases (84.9%) for a follow-up time of 6 60 months.Total removal of the lesion was achieved in 68 cases (67.3%) and subtotal removal in 33 cases (32.7 %).Sixty-five cases had partial recurrence (64.4%) and 60 patients died due to tumor recurrence.Survival in patients with low grade gliomas (LGG) was significantly higher than that in patients with high grade gliomas (HGG).Patients with total tumor resection had a longer survival time than patients who had subtotal tumor resection.In the control LGG group,6-month survival was 96.7%,1-year survival was 73.3%,2-year survival was 53.3%,4-year survival was 36.7% and 5-year survival was 26.7%.In the control HGG group,survival at 6 months,1 year,2 years,4 year and 5 years was 83.3%,36.7%,13.3%,3%,0 respectively.When comparing survival between the control groups and study groups,there was no significant difference at 6 months (P >0.05),but survival at 1 year,2 years,4 year and 5 years was different (P <0.05).Conclusions Intraoperative ultrasonography-guided resection of cerebral gliomas helps the surgeon to understand the relationship between the lesion and the surrounding structures,helps to protect normal brain tissue and increase the safety of surgery.It is of value in improving the total resection rate of tumors and the patient's survival time. Key words: Ultrasonography ; Glioma ; Survival rate

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