Evaluation of Interventional Therapy in the Combined Congenital Heart Diseases: Analysis of 11 Cases.

Abstract

Objective To investigate methods of interventional catheterization for combined congenital heart disease and evaluate its efficacy and safety in children. Methods From January 2008 to December 2008, 11 cases (3 boys and 8 girls) underwent transcatheter intervention for combined congenital heart disease, including 3 patients with ventricular septal defect(VSD) and patent ductus arteriosus(PDA), 3 with atrial septal defect(ASD) and pulmonary stenosis(PS), 2 with atrial septal defect and patent ductus arteriosus, 2 with patent ductus arteriosus and coarctation of aorta (COA), 1 with atrial septal defect and ventricular septal defect. The average age of all cases was (4.08±2.64) years old, the youngest was 5 months old, the oldest was 10 years old. The sequence of transcatheter intervention for the combined malformations was in order of pulmonary stenosis or coarctation of aorta, ventricular septal defect, patent ductus arteriosus and atrial septal defect. Informed consent was obtained from all participants. Results 11 patients were treated successfully. The results of the left ventricular angiography and transthoracic echocardiography after the procedure showed that there was no residual shunt flow and occluders fixed well. 1 patient showed incomplete right bundle branch block (IRBBB) after interventional treatment, and electrocardiogram (ECG) showed normal after treatment with dexamethasone. Conclusion Transcatheter intervention for combined congenital heart diseases could obtain satisfactory results with appropriate indications and procedure manipulations. Key words: congenital heart defects; multiple defects; interventional treatment