Evaluation of internal and external factors for clinical applications of biogenic metallic nanoparticles in dentistry

Abstract

The study explored the use and clinical applications of biogenic metallic nanoparticles synthesized by green methods in dentistry. It focused on evaluating the internal and external factors that influence their efficacy and application, with the aim of identifying both the opportunities and limitations of these emerging technologies in the dental field. A systematic literature review was conducted following the PRISMA procedure. 19 scientific articles published between 2018 and 2023, obtained from the PubMed and Scopus databases, were analyzed. The articles were selected based on specific inclusion and exclusion criteria. In addition, a SWOT analysis was conducted with the help of five dental experts to assess the factors affecting the implementation and impact of metallic nanoparticles. The analysis revealed that the weaknesses identified in the application of metallic nanoparticles had a greater weight than the strengths, indicating the need to develop defensive strategies to address the weaknesses. Opportunities outweighed threats, suggesting that the positive aspects of nanomaterials could be amplified to mitigate negative impacts. It was concluded that continued research and optimization of green synthesis methods is crucial to improve clinical efficacy and reduce negative impacts. It was suggested that future research focus on refining these processes and further evaluating the clinical applications of these materials