EVALUATION OF INFLAMMATORY BIOMARKERS IN CHRONIC KIDNEY DISEASE ASSOCIATED WITH CARDIOVASCULAR DISEASE IN A TERTIARY CARE HOSPITAL OF WEST BENGAL

Abstract

Introduction: Factors responsible for cardiovascular disease (CVD) become operational from the early course of CKD and are spread over the entire spectrum of it. The relative risks of cardiovascular events are inversely related to the estimated glomerular ltration rate (eGFR). A patient with CKD is more likely to die from CVD rather than CKD which denotes high burden of CVD in subpopulation and need for early intervention to reduce mortality. Generally in the population, early CKD, atherosclerotic disease is predominant cardiovascular disease but as the CKD progresses the burden of non-atherosclerotic disease increases.Aims:To evaluate relation of Inammatory Biomarkers (IB) in CKD patients with and without ECG and Echocardiography evaluated LVH and IHD with hypokinetic or dyskinetic wall motion with specic ECG changes in KPCMCH. Materials and method: This study was conducted 18 months at KPC medical college and hospital jadavpur, kolkata-72. 100 patients were included in this study. Result: Our study showed that, majority number of patients were Abnormal [64 (87.7%)] in with Echo LVH compared to [16(59.3%)] without Echo LVH it was statistically signicant (p=0.0016) and we also found that, majority number of patients were Abnormal [64(87.7%)] in with Echo LVH compared to [17 (63.0%)] it was statistically signicant (p=0.0272). Conclusion:We concluded that the frequency and types of cardiovascular diseases associated with different stages of CKD, traditional risk factors in CVD associated with various stages of CKD