Evaluation of Inflammation Markers and Pregnancy Outcomes of Patients Undergoing Intrauterin Insemination (IUI) for Unexplained Infertility

Abstract

Aim: This study aimed to compare the inflammatory markers in patients who had ovulation induction with clomiphene citrate (CC) and who underwent intrauterine insemination (IUI) due to unexplained infertility in patients who could get pregnant and who could not. Materials and Method: The study included 125 females with unexplained infertili-ty who underwent ovulation induction with CC and who underwent IUI at the Health Sciences University Ankara Etlik Zübeyde Hanım Gynecology Training and Research Hospital Assisted-Reproduction Therapy Clinic between July 2019 and December 2019. Of the patients, 104 (83.2%) of them could not get pregnant as a result of IUI, and 21 (16.8%) females got pregnant. Hemogram parameters collected from patients on the day of IUI were recorded. Results: In terms of age, infertility duration, BMI, gravida, parity, number of living children, abortion and stillbirth numbers, no statistically significant difference was found between the two patient groups which were created based on getting pregnant or not (p>0.05). No significant difference was found between the groups in terms of serum estrogen, progesterone, follicle-stimulating hormone (FSH), luteinizing hor-mone (LH), thyroid stimulating hormone (TSH), prolactin, and anti-mullerian hor-mone (AMH) levels, hemoglobin, BM, neutrophil count, lymphocyte count, platelet count, MPV, CRP, and P/L ratio (p>0.05). A statistically significant difference was found in terms of N/L ratio (p