Evaluation of Immune Status to Measles in Vaccinated Population in Tehran, by Enzyme-linked Immunosorbent Assay and the Hemagglutination Inhibition Techniques (1386-1387)

Abstract

Background and Aims: Measles remains one of the leading causes of childhood morbidity and mortality in developing countries and is still a major public health concern in developed countries. Although live attenuated vaccine is used throughout the world, out breaks of disease still occur in many countries including Iran. Methods: The present study was performed to evaluate the immune status against measles after the mass campaign vaccination in 2003. Results: In this study, Approximately 172 sera were analysed by ELISA and HI tests. The results indicated, 162 were positive (94.2%) and 10 were negative (5.8%) by HI test and 165 were positive (95.5%) and 7 were negative (4.1%) by the ELISA test. Conclusion: Understanding measles outbreaks that occur after the initiation of measles elimination efforts will be critical in refining the strategies for measles elimination.