Abstract

Evaluation of Immune Boosting Properties and Combating of Multiple Respiratory Viral Infections by fifteen Euphorbiaceae Plant Extracts

Highlights

  • Interest in a large number of traditional natural products has increased.[1,2] Natural products, such as hydroalcoholic and aqueous extracts, use in allopathic medicine, continue to provide bioactive agents because of the unmatched availability of chemical diversity.[2]

  • The serum of the vaccinated chicks treated with B. distacha has recorded the highest hemagglutination inhibition (HI) titers (7.1 and 8.3 log2) at the day of 28 post vaccination with high protection percentage (100 and 90%) post Newcastle disease virus (NDV) and avian influenza virus (AIV) H5N1 challenge, respectively

  • The serum of the vaccinated chicks treated with B. distacha has recorded the highest HI titers (7.1 log[2] and 8.3 log2) with high protection percents (100 and 90%) post NDV and AIV H5N1 challenge, respectively (Tables 3 and 4)

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Summary

Introduction

Interest in a large number of traditional natural products has increased.[1,2] Natural products, such as hydroalcoholic and aqueous extracts, use in allopathic medicine, continue to provide bioactive agents because of the unmatched availability of chemical diversity.[2]. Outbreaks of influenza virus infections in commercial poultry flocks appeared to be associated with severe clinical signs, variable high mortality (20%- 65%) and high reduction in egg production (up to 75%) as reported by Suarez (2008).[7] vaccines have long been available and administered to control these respiratory viral pathogens, they remain an ongoing threat to commercial flocks Vaccines against both viruses do not provide sterile immunity, and in many areas of the world vaccines are used to prevent losses from sickness and death.[6] Endemicity of NDV and AI circulation in poultry especially in Egypt could further aggravate the current situation.

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