Abstract

The current experiment was carried out to observe and analyze the effects of three orthodontic appliances combined with minocycline on periodontitis and inflammatory factors of gingival crevicular fluid. the patients included in this study were 180 patients with dental crowding treated in our hospital. They were divided into three groups, namely the invisible orthodontic appliance group (n=60), self-ligation orthodontic appliance group (n=60), traditional ligation bracket group (n=60), all of which were applied with minocycline therapy. The therapeutic effects of the three groups were observed. after three months of treatment, the periodontal index of each group showed an upward trend (p<0.05). At six months to one year, the periodontal index of the self-ligation orthodontic appliance group and conventional ligation bracket group was higher than that of the invisible orthodontic appliance group, p<0.05. After treatment, the expression of IL-1β and TNF-α increased for the three groups, p<0.05; the self-ligation orthodontic appliance group and the traditional ligation bracket group were the same as the invisible orthodontic appliance group in at 24 months, p>0.05. in the early stage of orthodontic treatment, the invisible orthodontic appliance can keep the oral cavity in a clean and hygienic state. However, after 18 months of orthodontic treatment, all three orthodontic treatments did not have a significant impact on oral hygiene.

Highlights

  • The important causes of gingivitis and periodontitis are dental plaque and toxin release, which bring an impact on patients' normal life quality to a different extent

  • The current experiment was carried out to observe and analyze the effects of three orthodontic appliances combined with minocycline on periodontitis and inflammatory factors of gingival crevicular fluid. the patients included in this study were 180 patients with dental crowding treated in our hospital

  • They were divided into three groups, namely the invisible orthodontic appliance group (n=60), self-ligation orthodontic appliance group (n=60), traditional ligation bracket group (n=60), all of which were applied with minocycline therapy

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Summary

Introduction

The important causes of gingivitis and periodontitis are dental plaque and toxin release, which bring an impact on patients' normal life quality to a different extent. Studies show that the development of dental plaque is closely related to environmental factors and individual factors, which are mainly reflected in oral hygiene, diet, saliva quality and fluoride exposure. Orthodontic appliance components (bracket, arch wire, and ligation wire) can produce a brushing dead corner [1,2], so that a large number of bacterial plaques may be accumulated, resulting in gingivitis and decalcification of hard tissues (Figure 1). Some studies have shown that during the assessment period of the impact of different orthodontic appliances on microbial flora and periodontal tissue, if the observation time is short, the changes of periodontal tissue inflammation will not be reflected [3,4]. This study analyzed the long-term effects of minocycline in combination with three kinds of orthodontic appliances (invisible orthodontic appliance, self-ligation orthodontic appliance and traditional ligation bracket) on periodontitis on and gingival crevicular fluid inflammatory factors, which provides a basis for clinical selection of orthodontic appliance

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