Evaluation of hydromethanolic extract and aglycone fraction of Actiniopteris semiflabellata for antioxidant activity

Abstract

Actiniopteris semiflabellata Pic-Ser grows in Yemen and is used by the local population for wounds and burns. The goal of the current study was to assess the Actiniopteris semiflabellata's chemical composition and antioxidant activity. Phenols, flavonoids, triterpenes and sterols were identified in the hydromethanolic extract and in the aglycone fraction, while carbohydrates were only found in the hydromethanolic extract. In the hydromethanolic extract and the aglycone fraction, the total phenolic content was evaluated as 17.73 mg/g and 7.22 mg/g respectively, while the total flavonoid content was 11.21 mg/g and 4.13 respectively. Studied extract and fraction exhibited antioxidant activity by TLC bioautography and DPPH radical scavenging activity assay. The IC50 values for the hydromethanolic extract and the aglycone fraction were 79.64 and 148.60 µg/ml respectively. These results confirm the traditional use and are useful for further study of this plant, in addition, it may be a good source of natural antioxidants.