Abstract
AbstractPhytase inclusion in phosphorus (P) deficient diet increases the bioavailability of nutrients and plays, indirectly, a role in biological function of many metabolic processes. The possibility of using phytase in diet might influence immune, growth and blood performances of animals. The objective of the study was to assess the effect of local bacterial phytase on humoral immunity in association with weight and blood characteristics of infectious bursal disease (IBD) vaccinated broilers. Male-day-old Cobb-broilers were assigned into four groups based on phytase treatments (0, 500, 1,000 and 1,500 fitase units per kg of diet) with 12 cages comprising three replicates per treatment, each treatment containing 15 birds. They were vaccinated with an IBD vaccine (IBD UPM93) and were fed formulating P (0.19%) deficient diet from 1 to 42 day of age. Results indicated that although serum IBD antibody, IgM, and IgG were not increased, mucosal IgA contents were increased with increasing phytase doses. Data on ...
Highlights
The enzyme phytase is a special class of phosphomonoesterase that is capable of catalyzing the sequential release of phosphate group from phytin in plant materials to yield inorganic phosphorus (P) and lower phosphorylated myo-inositol derivatives and decreases the phytin P disposal in nature (International Union of Biochemistry, 1979; Wyss et al, 1999)
Bacterial phytase The locally produced, rice bran fermented, crude and liquid, bacterial phytase synthesized from Enterobacter sakazaki ASUA273 was obtained from Standards and Industrial Research Institute of Malaysia (SIRIM) and the experiment was conducted at Faculty of Veterinary Medicine of Universiti Putra Malaysia
Effects on humoral immunity At weekly, the effects of locally produced bacterial phytase on Ab of infectious bursal disease virus (IBDV), IgM, IgA and IgG in broiler chickens are shown in Tables 2–5, respectively
Summary
The enzyme phytase is a special class of phosphomonoesterase (myo-inositol-hexakisphosphate phosphohydrolase) that is capable of catalyzing the sequential release of phosphate group from phytin (phytic acid and phytate) in plant materials to yield inorganic phosphorus (P) and lower phosphorylated myo-inositol derivatives and decreases the phytin P disposal in nature (International Union of Biochemistry, 1979; Wyss et al, 1999). Phytin is ubiquitous among plant components, comprising 1–5% (w/w) of cereal grains, oilseeds, legumes, pollen, and nuts (Gibson & Ullah, 1990) It is often considered an anti-nutrient because of its highly reactivity and readily forms less soluble complexes with Ca, Fe, Mg, Cu, Zn, proteins and/or amino acids in the small intestine and, less likely to interact with phytase (Ravindran, Cowison, & Selle, 2008; Selle & Ravindran, 2007). Phytase addition in low P diet may theoretically, influences chicken health in terms of immune responses in association with blood and growth characteristics It has attracted great attention from both researchers and entrepreneurs in the areas of nutrition, environmental protection, and biotechnological application
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