Evaluation of Hormones and Trace Elements in Women with Unexplained Infertility

Abstract

This study aims to Evaluation of prolactin (PRL), thyroid stimulating hormone (TSH), luteinizing (LH)and Follicle stimulating hormone(FSH)and trace elements (iron and copper) in women with unexplained infertility (UI). 60 women with unexplained infertility as well as (40) women with polycystic ovarian syndrome (PCOS) aged (20-35) year were included in this study. The women were divided according the type of infertility into primary and secondary groups (1oUI, 2oUI, 1oPCO and 2oPCO) respectively. Fifty healthy fertile women with the same age were included in this study as a control group. The results showed a significant increase in serum of Prolactin, TSH, LH levels in the two groups of women with explained infertility (pcos) compared to control and the two groups of women with unexplained infertility. In contrast no significant differences in Prolactin, TSH, FSH and LH levels in women with unexplained infertility in comparison with the control.Serum levels of iron and copper significantly increase in unexplained infertility groups in comparison with women with explained infertility and control groups. This study concluded that is Prolactin, TSH and LH hormone are not associated statistically with unexplained female infertility. The increase in Cu and iron may have an important etiological role in the pathogenicity of unexplained infertility.