Abstract
Abstract Objective Depressive disorders have an overall prevalence of 12.1%, which is clinically very significant. This study is taken up to understand the concept of the causes of depressive disorders, to understand the miasmatic state of depressive disorders and to determine the efficacy of homoeopathic medicines in the management of depressive disorders. Methods A prospective, non-comparative, open-label observational study was done at Multi-Specialty Clinic and Research Centre of The Andhra Pradesh Homoeopathic Association from 2009 to 2012. Patients aged between 15 and 30 years, presenting with symptoms of depressive disorders, were screened for inclusion and exclusion criteria and a total of 207 cases were enrolled for the study. The characteristic symptoms of the patients were recorded, repertorised, miasmatic diagnosis done and medicines prescribed based on individualisation of patient, with the help of materia medica. Hamilton depression rating scale (HAM-D) was used to assess the treatment. The parameter of improvement was - Marked improvement - 75% and above; outcome. Moderate improvement - 50% and above; Mild improvement - 25%. Results Out of 207 enrolled patients, 32 cases were dropout, while total 175 cases were analysed. The significant difference (p = 0.0001, p < 0.05) in the mean scores of HAM-D using paired t-test was observed at the end of the study; marked improvement was seen in 39 cases; moderate improvement was seen in 76; mild improvement was seen in 34 cases; no improvement was seen in 26 cases. Remedies such as Ignatia, Nat mur, Nux vomica, Staphysagria, Arsenicum album and Lycopodium were found to have a positive role. Conclusion The study showed positive and encouraging results of homoeopathic intervention in the management of patients suffering from depressive disorders as measured by HAM-D scale.
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