Evaluation of high- dose atorvastatin- mediated shock wave sonoporation therapy on advanced atherosclerosis with vulnerable atheromatous plaque using magnetic resonance imaging and histopathology

Abstract

Background and Aims : Mature or immature atheroma within a thin- fibrous cap accompanied by foam cells, extracellular lipid- laden cells and a low probability of calcification, is called vulnerable atheromatous plaque. In this study, we investigated the feasibility of imaging of plaque using Magnetic Resonance Imaging (MRI) technique.