Evaluation of Herbal Formulation of Saaranai Chooranam Through Fourier Transform Infrared Spectroscopic Study

Abstract

Background: The Siddha system of medicine is purely scientific and the peculiar complex system of science and philosophy. Fourier Transform Infrared Spectroscopy (FTIR) is certainly one of the most important analytical techniques for herbal medicine. FTIR can be implemented during herbal drug development in production for process monitoring or in quality control laboratories. Aim & Objective: The aim of study is to evaluate the morphology and elemental characterization of the Saaranai chooranam. The functional groups of their formulations are analysed through FTIR spectroscopy and the biological roles of the functional groups are discussed in this study. Materials and methods: The raw drugs is collected and purified as per Siddha literature. Drug Saaranai chooranam, which has been illustrated in the text Dr.S.Venkattarajan, Akasthiyar-2000, Part – III, Page: 102, for the management of Raththa Kothippu (Systemic Hypertension). Results: The Fourier Transform Infrared Spectroscopy compounds showed the presence of functional groups O-H Stretching (Alcohol), C-H Stretching (Alkane), O=C=O Stretching (Carbon dioxide), C-C bending (Alkene), O-H bending (Carboxylic acid), C-O Stretching (Aromatic ester), C-O Stretching (Tertiary alcohol), S=O Stretching (Sulfoxide), C-H bending (1,2-disubstituted) and C-1 Stretching (Halo compound) which ensures the therapeutic effect of the drug. Conclusion: The instrumental analysis FT-IRS study of Saaranai chooranam is the presence of functional groups through the stretch and bends which is responsible for its functional activity. The functional groups in Saaranai chooranam have diuretic and nervin tonic activities. This will ensure the efficacy and therapeutic effect of the drug.