Evaluation of healing and anti-plaque efficacy of antioxidant mouthrinse in patients with gingival inflamation – A single blind clinical study

Abstract

: To evaluate the clinical efficacy of healing as well as anti plaque activity of an antioxidant mouthrinse containing sodium hyaluronate, coenzyme Q10, tea tree oil and aloe vera as active ingredients in a subject population of established clinical gingivitis. A single blind study was conducted among 45 participants, all of whom were in the age group of 18‑60 years. The study subjects were randomly divided into three groups of 15 each. The control group where only oral hygiene instructions were given. Group B1 in which the participants underwent oral prophylaxis at baseline, day 7 and day 14. Group B2 where the participants were given the antioxidant mouthrinse to use thrice daily in addition to undergoing oral prophylaxis at baseline, day 7 and day 14. The clinical parameters assessed were the probing pocket depth, Plaque Index by Sillness and Loe (1964) and Gingival Index by Loe and Sillness (1963). These were assessed at baseline, day 7 and day 14 for all the 3 groups. The results were found to be statistically significant at 14 days interval of plaque and gingival inflammation reduction in the B2 group as compared to the other two groups, however, with regard to reduction of periodontal depth, the result was not found to be significant. This study supports the effectiveness of herbal constituents based antioxidant mouthwash in its role as an antiplaque and healing agent. It should be explored as a cost‑effective, long‑term antiplaque rinse with prophylactic and therapeutic benefits.