Abstract
In the present study the genotoxic, mutagenic and antitumor effects of 2-amino-2-thiazoline (R), L-thioproline (N) and 2-amino-2-thiazoline e-formylaminocaproate (FAT) as well as their influence on bacterial growth and activity of the extracellular protease are discussed. On the basis of our study the following conclusions may be drawn: the investigated compounds, except N, had no strongly expressed genotoxic activity and none of them was found to be mutagenic. R and FAT were insignificantly toxic on bacterial growth, all compounds were ineffective against transplanted tumors and did not change the rate of the biosynthesis of Bacillus subtilis extracellular neutral protease.
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