Abstract
PurposeWe investigated whether laser speckle flowgraphy (LSFG) results are comparable in both eyes and whether it is useful in the diagnosis of disparity in ocular ischemic syndrome (OIS) patients.MethodsWe compared the mean blur rate (MBR) value for various fundus regions in both eyes of 41 healthy subjects and 15 internal carotid artery occlusion (ICAO) cases. We calculated the standard value of the Laterality Index (LI), which was the MBR comparison of both eyes in each of the regions, in the control subjects. We then investigated the correlation between both eyes for the LIs in the entire fundus, the degree of ICAO and visual function.ResultsThe disparity of the LIs in both eyes was least in the entire area of the fundus in control subjects and there was a significant correlation between both eyes of the 41 healthy individuals (P = 0.019). Significant correlations were found for the LI, visual acuity and degree of ICAO. The specificity and sensitivity of LI in the entire area was 93.8% and 100%, respectively.ConclusionsLSFG revealed normal individuals have symmetrical fundus blood flow. LSFG could detect OIS and might be a useful tool for detecting disparities in fundus blood flow.
Highlights
Ocular ischemic syndrome (OIS), which accompanies ischemic ophthalmopathy, is caused by a decrease in ocular blood flow that is the direct result of diminished ophthalmic artery blood pressure due to occluded regions in the internal carotid artery (ICA).[1]
The disparity of the Laterality Index (LI) in both eyes was least in the entire area of the fundus in control subjects and there was a significant correlation between both eyes of the 41 healthy individuals (P = 0.019)
Significant correlations were found for the LI, visual acuity and degree of internal carotid artery occlusion (ICAO)
Summary
Ocular ischemic syndrome (OIS), which accompanies ischemic ophthalmopathy, is caused by a decrease in ocular blood flow that is the direct result of diminished ophthalmic artery blood pressure due to occluded regions in the internal carotid artery (ICA).[1]. In OIS patients, severe carotid artery disease can cause transient visual loss as a result of choroidal hypoperfusion[2] or retinal or optic nerve infarction. [8] Many of these patients stated that their vision sometimes felt patchy or that they noticed sectorial loss. These conditions were found to be caused by either emboli or vasospasms of the carotid artery or ophthalmic artery. These conditions were found to be caused by either emboli or vasospasms of the carotid artery or ophthalmic artery. [9,10,11] there have been no reports on the relationship among visual symptoms and choroidal blood flow
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