Abstract
The objective : to assess functional disorders in various models of clinical situations in patients with the severe course of tuberculosis. Subjects and methods . Functional disorders were assessed in 154 tuberculosis patients (HIV positive or HIV negative) with a severe course of the disease, distributing them according to clinical situation models. 4 models of clinical situations for such patients were proposed: M 1 - patients with chronic forms of tuberculosis (after 2 or more treatment failures), with complications, but no severe immunodeficiency; patients with acute progressive tuberculosis without lesions of the central nervous system (CNS); M 2 - HIV positive and HIV negative patients with acute progressive tuberculosis without lesions of the central nervous system; M 3 - patients with tuberculosis and meningitis (meningoencephalitis) of various etiologies; M4 - patients with tuberculosis and chronic progressing diseases of a therapeutic profile. Results. The scale for assessing functional deficits in tuberculosis patients allows determining the type and severity of functional disorders as well as mobility, the ability to self-service and communication in patients with a severe course of the disease. The severity of functional disorders differs in patients from different models, it is the smallest with M 1 model - a chronic course of tuberculosis, and it is the biggest in M 3 model - tuberculosis with central nervous system lesions. The proposed models can be the basis for development of differentiated management regimens for such patients and provision of care in TB units, estimation of the demand for auxiliary care products, analgesic and symptomatic therapy, as well as compilation of algorithms for medical personnel actions.
Highlights
Оценивали клинические и лабораторные признаки недостаточности внутренних органов, признаки нарушения общения, мобильности и способности к самообслуживанию с помощью «Шкалы оценки функционального дефицита у больных туберкулезом» [10]
Предложено 4 модели клинических ситуаций для больных туберкулезом с тяжелым течением заболевания, степень выраженности функциональных нарушений у них является наименьшей при модели М1 – хроническое течение туберкулеза, а наибольшей при М3 – туберкулез с поражением ЦНС
Summary
Functional disorders were assessed in 154 tuberculosis patients (HIV positive or HIV negative) with a severe course of the disease, distributing them according to clinical situation models. 4 models of clinical situations for such patients were proposed: M1 – patients with chronic forms of tuberculosis (after 2 or more treatment failures), with complications, but no severe immunodeficiency; patients with acute progressive tuberculosis without lesions of the central nervous system (CNS); M2 – HIV positive and HIV negative patients with acute progressive tuberculosis without lesions of the central nervous system; M3 – patients with tuberculosis and meningitis (meningoencephalitis) of various etiologies; M4 – patients with tuberculosis and chronic progressing diseases of a therapeutic profile. Functional disorders were assessed in 154 tuberculosis patients (HIV positive or HIV negative) with a severe course of the disease, distributing them according to clinical situation models. 4 models of clinical situations for such patients were proposed: M1 – patients with chronic forms of tuberculosis (after 2 or more treatment failures), with complications, but no severe immunodeficiency; patients with acute progressive tuberculosis without lesions of the central nervous system (CNS); M2 – HIV positive and HIV negative patients with acute progressive tuberculosis without lesions of the central nervous system; M3 – patients with tuberculosis and meningitis (meningoencephalitis) of various etiologies; M4 – patients with tuberculosis and chronic progressing diseases of a therapeutic profile. For citations: Pyanzova T.V., Vasilyeva I.А., Dzhangildin Yu.T. Evaluation of functional disorders in tuberculosis patients with the severe course of the disease.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
