Abstract
Mulberry, as medicinal and edible traditional Chinese herb， has many physiological functions. The present study aims to evaluating the antioxidant activity in vitro and immune modulation of mulberry extracts (ME). The antioxidant ability of ME was comprehensively evaluated by different systems, including the scavenging rates of DPPH and ABTS radical. The mice spleen lymphocyte transformation experiment and the mice peritoneal macrophage phagocytosis chicken red blood cells test were used to observe the effects of ME on specific cellular immunity and nonspecific immunity. The results showed that the IC50 of ME on DPPH and ABTS radical were 521.10 and 1049.44 μg/mL, respectively. In addition, ME can promote the proliferation of spleen lymphocytes and strengthen the phagocytic function of monocyte macrophages. Mulberry has antioxidant benefit and immune boosting effect, which provide a reference for more adequate development and utilization of mulberry resources.
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