Evaluation of first-trimester complete blood count inflammatory indices in placenta previa

Abstract

Aim: To evaluate systemic inflammation in pregnant women diagnosed with placenta previa (PP). First-trimester complete blood count indices of PP patients were assessed. Materials and Method: This cross-sectional study was conducted with 346 singleton pregnant women, including 115 PP cases (study group) and 231 healthy pregnant women (control group) who were operated on in a tertiary center for one year. The study group was then divided into two subgroups. Those who underwent peripartum hysterectomy due to placenta accreta spectrum (PAS) were determined as PAS-positive, and those without invasion were PAS-negative. Demographic and obstetric characteristics laboratory results were recorded retrospectively. Systemic immune-inflammation index (SII) and systemic inflammatory response index (SIRI) values were calculated. Data were presented as mean and standard deviation using the independent sample t-test. Results: The mean value of maternal age, body mass index, and gestational weeks at which hemograms were evaluated were similar between the study and control groups. While white blood cell and neutrophil counts were significantly higher in the PP group, red blood cell and hemoglobin counts were lower (p