Abstract

目前,原发性肝癌(HCC)患者的5年生存率尚不到10%.HCC易侵犯门静脉形成癌栓,几率高达30.0%~60.2%[1].门静脉癌栓(portal vein tumor thrombus,PVTT)形成被认为是影响HCC预后的独立因素[2].我科自2008年采用腔内植入125Ⅰ粒子条及支架联合经肝动脉化疗栓塞术(transcatheter arterial chemoembolization,TACE)治疗HCC合并门静脉主干癌栓取得了良好的疗效[3].但该疗法要求患者的门静脉二级分支血流必须通畅,部分晚期原发性肝癌患者往往出现广泛性PVTT,因门静脉二级分支血管闭塞,或癌栓超过肠系膜上静脉或脾静脉,无法放置内支架.故我们采用B超引导下经皮门静脉腔内125Ⅰ粒子条联合TACE治疗HCC合并PVTT. 关键词:癌,肝细胞;门静脉系统;125Ⅰ粒子;经动脉化疗栓塞术;癌栓

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