Evaluation of Efficacy of Platelet-Rich Fibrin (PRF) versus Alvogyl and Zinc Oxide and Eugenol (ZOE) packing in the Management of Alveolar Osteitis: A prospective randomized clinical study

Abstract

Purpose: The purpose of this research was to compare the effectiveness of platelet rich fibrin (PRF), alvogyl and zinc oxide/ eugenol (ZOE) intra-alveolar dressings for pain relief and socket healing (Epithelialization) in dry socket management and to study relevant epidemiological features.Patients and methods: A total of 45 patients with alveolar osteitis were randomly divided into three groups; Group (A) patients received PRF, Group (B) patients received Alvogyl and Group (C) patients received ZOE dressing. All the patients were evaluated for Pain (VAS), degree of inflammation, healthy granulation tissue formation and number of exposed socket walls (socket epithelialization) at 1st, 3rd, 7th, and 14th post-operative day. Results: Group A (PRF) showed better and faster socket healing than Group B and C. However, symptomatic pain relief was faster in Group B (Alvogyl) than in Group A and C.Conclusion: PRF in this study illustrates the promising results to be used effectively as the suitable dressing material in the management of alveolar osteitis. PRF treated cases showed a shorter time required for complete and fast clinical healing.