Evaluation of efficacy and safety of laparoscopic D3 radical correction with pelvic autonomic nerve preservation for rectal cancer

Abstract

Objective To investigate the safety and efficacy of laparoscopic D3 radical correction with pelvic autonomic nerve preservation for rectal cancer. Methods The clinical deta of 211 patients with rectal cancer underwent D3 radical correction with pelvic autonomic nerve preservation in our hospital from 2010 to 2014 were retrospectively analyzed, they were divided into two groups (laparoscopic group,n= 131; open group, n= 80), the statistical results of the two groups were compared. Results All the operated patients was successful, 211 cases were successfully completed surgery. The laparoscopic group mean operative time was(3.33±0.72)h, ambulation began within 1-4 days postoperatively, the average time for passage of flatus was(3.48±0.82) d, the median number of total lymph nodes removed was 14.94±3.41. The postoperative complications were observed in 16 of 131 cases(12.2%)including incision infection in 9 cases, Pulmonary infection in 2 cases, anastomotic fistula in 1 cases, anastomotic bleeding in 4 cases, no anastomotic fistula occurred. No significant difference in the number of total lymph nodes removed(P> 0.05) and the postoperative complications(P> 0.05) was observed between the two groups. Bowel flatus passed and hospital stay(P< 0.05) earlier(P< 0.01) in laparoscopic than that in open group. Operative time shorter(P< 0.01)in open than that in laparoscopic group.no significant difference in urinary dysfunction and sexual dysfunction after operation was observed between the two groups. Conclusion Laparoscopic D3 radical correction with pelvic autonomic nerve preservation for rectal cancer is feasible and safe, quick postoperative recovery, has the obvious advantage of minimally invasive, and the life quality of patients is higher. Key words: Rectal carcinoma; Laparoscope; D3 radical correction; Pelvic autonomic nerve preservation