Abstract
：Objective To evaluatethe early change of left ventricular (LV) systolic function in patients with type 2diabetes mellitus(T2DM) by ultrasound speckle tracking imaging. Methods Ninety-fivesubjects were included:40 T2DM with normal LV ejection fraction (LVEF≥50%,group A),20 T2DM with abnormal LVEF (LVEF 0.05), peak systolic circumferential strain of partsegments, average peak strain of each plane and global strain were reduced (P <50.05～0.001),and LV peak systolic rotation of all apical segments, peak systolic global rotation atthe levels of mitral annulus and apex,and peak systolic global twist were significantlyincreased (P <0.05～0.001). Compared with control group and group A,allLV systolic radial strain and circumferential strain parameters, LV systolic global andsegmental rotation and peak systolic global twist in group B were significantly reduced (P<0.05 ～ 0.001).Conclusions Speckle tracking imaging could be used to evaluate the early change of LVtorsional deformation and LV systolic function in T2DM. Key words: Echocardiography; Diabetes mellitus,type 2 ; Ventricularfunction,left; Speckle tracking imaging
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