Abstract

We assessed the use of high-resolution 18F-2-fluoro-deoxy-D-glucose (18FDG)-positron emission tomography (PET) in evaluating the presence of variable degrees of dynamic stress of the cervical spinal cord in 22 patients with cervical myelopathy. For this purpose, we examined the correlation between the average standardized uptake value (SUV) of 18FDG utilization rate of the cervical cord and neurological functional score before and after surgery. The average preoperative SUV of 18FDG utilization correlated significantly with the preoperative neurological score (P < 0.05) but did not correlate with the postoperative score (P = 0.08). The average SUV correlated with the rate of neurological improvement (P < 0.05) after surgery. Although the results suggest that high-resolution 18FDG-PET imaging may provide qualitative and quantitative estimates of impaired metabolic activity of the compromised cervical cord, at present, 18FDG-PET imaging does not provide a clear visualization of the cervical cord injury caused by dynamic stress of the cord.

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