Evaluation of Drug-Related Problems among Chronic Kidney Disease Patients by Clinical Pharmacist

Abstract

Background The prevalence of chronic kidney disease CKD in India is 17.2 with nearly 6 having Stage 3 CKD or worse. CKD patients are at greater risk for drug related problems DRPs due to high incidence of comorbidities.Aim of the study The main aim of this study was to investigate the prescription patterns and pinpoint the numerous DRPs resulting from the treatment in patients with CKD.Methods A prospective observational research was conducted including 60 patients with CKD. DRPs were found and grouped using the Pharmaceutical Care Network Europe categorization V 5.01 after the prescription pattern was examined.Results The study included a total of 60 patients with 68.3 of participants being males. The average age of the participants was 46 years. Diabetes mellitus 28.33 and hypertension 35 were found to be the two main associated comorbidities. The average number of prescriptions was 10.9 which indicates polypharmacy. Antibiotics were the most often prescribed class of medications 15.8. Medication interactions was found to be the most prevalent DRP 49.3 followed by drug choice issues 19.27 dose issues 8.96 drug usage issues 8.96 adverse reactions 1.20 and other difficulties 9.84. Lack of knowledge ranked the first among major causes of DRP 35 42.16 followed by drug use process 25 30.12.Conclusion Drug-related problems among CKD patients were high. Prompt identification and treatment of DRPs by the health care team can enhance the health and quality of life in these patients.