Abstract
Purpose: This study compares two LINAC-based techniques for treating multiple brain lesions using quantitative evaluation of plan dosimetric indices. Material and Methods: Twenty-one patients with a total of 168 targets were selected. All plans were designed with five non-coplanar arcs in the RayStation treatment planning system (TPS). The composite dose of Multiple Isocenter Multiple Targets (MIMT) was compared to that of single isocenter multiple targets (SIMT) by evaluating conformity indices, Paddick gradient-index (PGI), V8, V12, and Delivery Time (DT).
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