Evaluation of dosimetric functions for a new 169 Yb HDR Brachytherapy Source.

Abstract

169Yb has been recently used as an HDR brachytherapy source for cancer treatment. In this paper, dosimetric parameters of a new design of 169Yb HDR brachytherapy source were determined by Monte Carlo (MC) method and film dosimetry. In this new source, the radioactive core has been encapsulated twice for safety purposes. The calculations of dosimetric parameters carried out using MC simulation in water and air phantom. In order to exclude photon contamination's cutoff energy, δ was set at 10 keV. TG‐43U1 data dosimetric, including Sk, Λ, g(r), F(r, θ) was computed using outputs from the simulation and their statistical uncertainties were calculated. Dose distribution around the new prototype source in PMMA phantom in the framework of AAPM TG‐43 and TG‐55 recommendations was measured by Radiochromic film (RCF) Gafchromic EBT3. Obtained air kerma strength, Sk, and the dose rate constant, Λ, from simulation has a value of 1.03U ± 0.03 and 1.21 cGyh−1U−1 ± 0.03, respectively. The radial dose function was calculated at radial distances between 0.5 and 10 cm with a maximum value of 1.15 ± 0.03 at 5–6 cm distances. The anisotropy functions for radial distances of 0.5–7 cm and angle distances 0° to180° were calculated. The dosimetric data of the new HDR 169Yb source were compared with another reference source of 169Yb‐HDR and were found that has acceptable compatibility. In addition, the anisotropy function of the MC simulation and film dosimetry method at a distance of 1 cm from this source was obtained and a good agreement was found between the anisotropy results.