Abstract

Objectives:To assess the effect of two of the most commonly used sterilization techniques on 3D printed clinical objects.Materials & Methods:The two sterilization methods used in our hospital and investigated in this paper are: Steam heat and Gas plasma. Three objects were printed and tested in this study: a tooth replica, an orthognathic final splint, a surgical cutting guide for the purpose of mandible reconstruction. For each of the 3 objects, 4 copies were made: one original STL object, one copy of the object pre-sterilization, one copy of post-steam heat sterilization, and one copy of post-gas plasma sterilization. Each printed object was scanned using a high resolution CBCT protocol and the compared (morphologically and volumetrically).Results: At the level of volumetric changes, no difference was found between pre and post-sterilization for both methods evaluated. As for the morphological changes, only differences were noticed with the orthognathic splint object indicating deformation of the printed splints after sterilization. Larger differences were observed with heat sterilization, making it less reliable.Conclusion: Sterilization of dental objects to be used in a clinical setting may lead to deformation of the printed model, especially for heat sterilization. Further investigations are needed to confirm these findings.

Highlights

  • Additive manufacturing, rapid prototyping or three-dimensional (3D) printing is a growing technology which is changing the manufacturing industry [1]

  • Gas plasma sterilization is recommended to materials sensitive to temperature, humidity and which do not comply for Ethylene Oxide (EtO) sterilization can be sterilized using gas plasma

  • As for the accuracy of the heat sterilization, the percentage change in volume ranged from -0.6% to 1.5%

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Summary

Introduction

Rapid prototyping or three-dimensional (3D) printing is a growing technology which is changing the manufacturing industry [1]. The most common techniques are Stereolithography (SLA), Selective Laser Sintering (SLS), Fused Deposition Modeling (FDM), PolyJet Technology, and Laminated Object Manufacturing (LOM). Recent developments in medical imaging along with the developments in Computer Aided Design/Computer Aided Manufacturing (CAD/CAM) allowed the fast rise of 3D printing in medicine. Applications of 3D printing in the medical field vary from treatment planning, surgical guides, teaching models, educational tools to printing scaffolds for tissue engineering and direct printing of tissues and organs [1].

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