Evaluation of different staging methods on radical resection rate and prognosis of patients with hilar cholangiocarcinoma

Abstract

Objective To compare the Bismuth-Corlette typing, modified T-staging and Mayo staging system in predicting the radical resection rates and prognosis of patients with hilar cholangiocarcinoma (HCC). Methods The clinical data of 138 patients with hilar cholangiocarcinoma treated in the First Bethune Hospital of Jilin University were retrospectively analyzed. Three different staging methods were used. Results With increase in the classification level of the Bismuth-Corlette classification, the radical resection rate did not significantly decrease (P>0.05). The radical resection rates of stage T1, T2 and T3 in the modified T-staging system were 60.0% (27/45), 36.0% (10/28) and 14.0% (9/65) respectively (all P 0.05). However, there were significant differences among the survival rates in the various tumor staging levels using the Mayo Staging System. Conclusions The modified T-staging system and the Mayo staging system were more accurate than the Bismuth-Corlette typing system in predicting radical resection rates in patients with hilar cholangiocarcinoma. The Mayo staging system was superior to the Bismuth-Corlette typing system and the modified T-staging system in predicting prognosis of patients with hilar cholangiocarcinoma. Key words: Bile duct neoplasms; Prognosis; Bismuth-Corlette typing system; Modified T-staging system; Mayo staging system; Hilar cholangiocarcinoma; Radical resection