Abstract
Evaluation of Different Fractions of Garcinia kola Extracts against Multidrug Resistant Clinical Bacterial and Fungal Isolates
Highlights
The use of herbal produce in the treatment of various ailments continue to receive worldwide attention by researchers as traditional medicines derived from plants have become highly important as alternative medicines in the treatment of a huge number of diseases.[1,2] These plant derivatives are considered safe and more affordable for majority of the developing world
Out of all the isolates used two were resistant to colistin antibiotics, a drug regarded as the last resort to the treatment of multidrug resistant bacteria
It showed that all the A. baumannii isolates from either diabetic or sputum samples were susceptible to aqueous fraction followed by the butanol fraction, ethyl acetate fraction and hexane fraction
Summary
The use of herbal produce in the treatment of various ailments continue to receive worldwide attention by researchers as traditional medicines derived from plants have become highly important as alternative medicines in the treatment of a huge number of diseases.[1,2] These plant derivatives are considered safe and more affordable for majority of the developing world. The plant is grown in the humid regions of Western and Central Africa.[4,5] The tropical plant Garcinia belongs to the family Clusiaceae with origins said to be Asia, Australia, tropical and Southern Africa.[6] The seeds of the plant, bitter kola, are used by some tribes in Nigeria for various ceremonial celebrations such as weddings, child naming ceremonies amongst others At such celebrations, they are chewed as snacks[7] and there is no specific amount that can be chewed at a sitting due to it friendliness to the digestive system.[7] Chewing is believed to have a mechanical cleansing effect with the release of antimicrobial agents.[8] chewing of the seeds is reported to bring relief to coughs, colds and throat infections while earlier reports by Iwu[9] stipulated that the plant derivatives are used in the treatment of liver disorders and jaundice. The aqueous fraction showed better activities than the other fractions studied
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